Synthesis and biological evaluation of thiazolidine-2-thione derivatives as novel xanthine oxidase inhibitors

Xanthine oxidase (XO) is a key enzyme in the generation and development of hyperuricemia. Thiazolidine-2-thione, a typical heterocyclic compound, have been widely used in the field of drug synthesis. In this study, a series of novel thiazolidine-2-thione derivatives were synthesized as XO inhibitors...

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Detalles Bibliográficos
Autores principales: Wang, Mu-Xuan, Qin, Hong-Wei, Liu, Chao, Lv, Shen-Ming, Chen, Jia-Shu, Wang, Chun-Gu, Chen, Ying-Ying, Wang, Jia-Wei, Sun, Jin-Yue, Liao, Zhi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116648/
https://www.ncbi.nlm.nih.gov/pubmed/35584139
http://dx.doi.org/10.1371/journal.pone.0268531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116648/
https://www.ncbi.nlm.nih.gov/pubmed/35584139
http://dx.doi.org/10.1371/journal.pone.0268531

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