Polygenic score accuracy in ancient samples: Quantifying the effects of allelic turnover

Polygenic scores link the genotypes of ancient individuals to their phenotypes, which are often unobservable, offering a tantalizing opportunity to reconstruct complex trait evolution. In practice, however, interpretation of ancient polygenic scores is subject to numerous assumptions. For one, the g...

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Detalles Bibliográficos
Autores principales: Carlson, Maryn O., Rice, Daniel P., Berg, Jeremy J., Steinrücken, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116686/
https://www.ncbi.nlm.nih.gov/pubmed/35522704
http://dx.doi.org/10.1371/journal.pgen.1010170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116686/
https://www.ncbi.nlm.nih.gov/pubmed/35522704
http://dx.doi.org/10.1371/journal.pgen.1010170

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