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Polygenic score accuracy in ancient samples: Quantifying the effects of allelic turnover
Polygenic scores link the genotypes of ancient individuals to their phenotypes, which are often unobservable, offering a tantalizing opportunity to reconstruct complex trait evolution. In practice, however, interpretation of ancient polygenic scores is subject to numerous assumptions. For one, the g...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116686/ https://www.ncbi.nlm.nih.gov/pubmed/35522704 http://dx.doi.org/10.1371/journal.pgen.1010170 |