Polycomb Repressive Complexes: Shaping Pancreatic Beta-Cell Destiny in Development and Metabolic Disease

Pancreatic beta-cells secrete the hormone insulin, which is essential for the regulation of systemic glucose homeostasis. Insufficiency of insulin due to loss of functional beta-cells results in diabetes. Epigenetic mechanisms orchestrate the stage-specific transcriptional programs that guide the di...

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Detalles Bibliográficos
Autores principales: Varghese, Sneha S., Dhawan, Sangeeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116887/
https://www.ncbi.nlm.nih.gov/pubmed/35602600
http://dx.doi.org/10.3389/fcell.2022.868592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116887/
https://www.ncbi.nlm.nih.gov/pubmed/35602600
http://dx.doi.org/10.3389/fcell.2022.868592

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