Cargando…

Blocking C3d(+)/GFAP(+) A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke

Astrocytes play an essential role in the modulation of blood-brain barrier function. Neurological diseases induce the transformation of astrocytes into a neurotoxic A1 phenotype, exacerbating brain injury. However, the effect of A1 astrocytes on the BBB dysfunction after stroke is unknown. Adult mal...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qi, Liu, Chang, Shi, Rubing, Zhou, Shiyi, Shan, Huimin, Deng, Lidong, Chen, Tingting, Guo, Yiyan, Zhang, Zhijun, Yang, Guo-Yuan, Wang, Yongting, Tang, Yaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116904/
https://www.ncbi.nlm.nih.gov/pubmed/35656116
http://dx.doi.org/10.14336/AD.2021.1029