Cargando…

Blocking C3d(+)/GFAP(+) A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke

Astrocytes play an essential role in the modulation of blood-brain barrier function. Neurological diseases induce the transformation of astrocytes into a neurotoxic A1 phenotype, exacerbating brain injury. However, the effect of A1 astrocytes on the BBB dysfunction after stroke is unknown. Adult mal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qi, Liu, Chang, Shi, Rubing, Zhou, Shiyi, Shan, Huimin, Deng, Lidong, Chen, Tingting, Guo, Yiyan, Zhang, Zhijun, Yang, Guo-Yuan, Wang, Yongting, Tang, Yaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116904/ https://www.ncbi.nlm.nih.gov/pubmed/35656116 http://dx.doi.org/10.14336/AD.2021.1029

Ejemplares similares

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
por: Jones, Jeffrey R., et al.
Publicado: (2018)

Optogenetic Activation of Astrocytes Reduces Blood-Brain Barrier Disruption via IL-10 In Stroke
por: Suo, Qian, et al.
Publicado: (2023)

GFAP expression in injured astrocytes in rats
por: Zhang, Shuquan, et al.
Publicado: (2017)

Crosstalk of Astrocytes and Other Cells during Ischemic Stroke
por: He, Tingting, et al.
Publicado: (2022)

Oligodendrocyte Precursor Cells Transplantation Improves Stroke Recovery via Oligodendrogenesis, Neurite Growth and Synaptogenesis
por: Li, Wanlu, et al.
Publicado: (2021)

Beyond the GFAP-Astrocyte Protein Markers in the Brain
por: Jurga, Agnieszka M., et al.
Publicado: (2021)

In Vivo Two-Photon Imaging of Astrocytes in GFAP-GFP Transgenic Mice
por: Guo, Dongjun, et al.
Publicado: (2017)

BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke
por: Huang, Shuxian, et al.
Publicado: (2021)

Identification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation
por: Ito, Kenji, et al.
Publicado: (2016)

Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes
por: Tatsumi, Kouko, et al.
Publicado: (2018)

Fingolimod Inhibits Inflammation but Exacerbates Brain Edema in the Acute Phases of Cerebral Ischemia in Diabetic Mice
por: Li, Wanlu, et al.
Publicado: (2020)

New Insights into GFAP Negative Astrocytes in Calbindin D28k Immunoreactive Astrocytes
por: Xu, Jie
Publicado: (2018)

Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model In Vitro
por: Zhao, Lina, et al.
Publicado: (2020)

Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke
por: Wang, Cheng, et al.
Publicado: (2022)

Age, environment, object recognition and morphological diversity of GFAP-immunolabeled astrocytes
por: Diniz, Daniel Guerreiro, et al.
Publicado: (2016)

Automated detection of GFAP-labeled astrocytes in micrographs using YOLOv5
por: Huang, Yewen, et al.
Publicado: (2022)

Immunoreactivity to astrocytes in different forms of dementia: High prevalence of autoantibodies to GFAP
por: Barthel, Paula Charlotte, et al.
Publicado: (2023)

Enhanced Expression of Markers for Astrocytes in the Brain of a Line of GFAP-TK Transgenic Mice
por: Zhang, Xiaoqin, et al.
Publicado: (2017)

Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus
por: Salois, Garrick, et al.
Publicado: (2016)

Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice
por: Anderova, Miroslava, et al.
Publicado: (2014)

Correction: Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice
Publicado: (2015)

Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve
por: Ling, Yik Tung Tracy, et al.
Publicado: (2020)

Distribution of GFAP in Squamata: Extended Immunonegative Areas, Astrocytes, High Diversity, and Their Bearing on Evolution
por: Lõrincz, Dávid, et al.
Publicado: (2020)

Roles of Ependymal Cells in the Physiology and Pathology of the Central Nervous System
por: Deng, Shiyu, et al.
Publicado: (2023)

M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice
por: Li, Zongwei, et al.
Publicado: (2021)

Astrocyte Specificity and Coverage of hGFAP-CreERT2 [Tg(GFAP-Cre/ERT2)13Kdmc] Mouse Line in Various Brain Regions
por: Park, Yongmin Mason, et al.
Publicado: (2018)

Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion
por: Hu, Xiaowen, et al.
Publicado: (2022)

GFAP at 50
por: Messing, Albee, et al.
Publicado: (2020)

Gfap and Osmr regulation by BRG1 and STAT3 via interchromosomal gene clustering in astrocytes
por: Ito, Kenji, et al.
Publicado: (2018)

Erratum in: Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve
Publicado: (2020)

Increases in GFAP immunoreactive astrocytes in the cerebellar molecular layer of young adult CBA/J mice
por: Tyszkiewicz, Cheryl, et al.
Publicado: (2021)

CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage
por: Hyun, Jae-Won, et al.
Publicado: (2022)

STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease
por: Hagemann, Tracy L., et al.
Publicado: (2023)

Plasma GFAP in Parkinson’s disease with cognitive impairment and its potential to predict conversion to dementia
por: Tang, Yilin, et al.
Publicado: (2023)

Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer
por: Gao, Longfei, et al.
Publicado: (2019)

Glial Fibrillary Acidic Protein (GFAP): Neuroinflammation Biomarker in Acute Ischemic Stroke
por: Amalia, Lisda
Publicado: (2021)

Intermediate filaments of zebrafish retinal and optic nerve astrocytes and Müller glia: differential distribution of cytokeratin and GFAP
por: Koke, Joseph R, et al.
Publicado: (2010)

HIV Nef Expression Down-modulated GFAP Expression and Altered Glutamate Uptake and Release and Proliferation in Astrocytes
por: Wilson, Kelly M., et al.
Publicado: (2023)

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
por: Yun, Seung Pil, et al.
Publicado: (2018)

Oral Semaglutide
por: Bui, Vinh, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cak8vkekutur8irqv0uga750al