Development of a clinical polygenic risk score assay and reporting workflow

Implementation of polygenic risk scores (PRS) may improve disease prevention and management but poses several challenges: the construction of clinically valid assays, interpretation for individual patients, and the development of clinical workflows and resources to support their use in patient care....

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Detalles Bibliográficos
Autores principales: Hao, Limin, Kraft, Peter, Berriz, Gabriel F., Hynes, Elizabeth D., Koch, Christopher, Korategere V Kumar, Prathik, Parpattedar, Shruti S., Steeves, Marcie, Yu, Wanfeng, Antwi, Ashley A., Brunette, Charles A., Danowski, Morgan, Gala, Manish K., Green, Robert C., Jones, Natalie E., Lewis, Anna C. F., Lubitz, Steven A., Natarajan, Pradeep, Vassy, Jason L., Lebo, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117136/
https://www.ncbi.nlm.nih.gov/pubmed/35437332
http://dx.doi.org/10.1038/s41591-022-01767-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117136/
https://www.ncbi.nlm.nih.gov/pubmed/35437332
http://dx.doi.org/10.1038/s41591-022-01767-6

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