Extended intergenic DNA contributes to neuron-specific expression of neighboring genes in the mammalian nervous system

Mammalian genomes comprise largely intergenic noncoding DNA with numerous cis-regulatory elements. Whether and how the size of intergenic DNA affects gene expression in a tissue-specific manner remain unknown. Here we show that genes with extended intergenic regions are preferentially expressed in n...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaura, Ravneet, Yeh, Ssu-Yu, Montanera, Kaitlin N., Ialongo, Alyssa, Anwar, Zobia, Lu, Yiming, Puwakdandawa, Kavindu, Rhee, Ho Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117226/
https://www.ncbi.nlm.nih.gov/pubmed/35585070
http://dx.doi.org/10.1038/s41467-022-30192-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117226/
https://www.ncbi.nlm.nih.gov/pubmed/35585070
http://dx.doi.org/10.1038/s41467-022-30192-z

Ejemplares similares