AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis

The RAS–BRAF signaling is a major pathway of cell proliferation and their mutations are frequently found in human cancers. Adenylate kinase 2 (AK2), which modulates balance of adenine nucleotide pool, has been implicated in cell death and cell proliferation independently of its enzyme activity. Rece...

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Detalles Bibliográficos
Autores principales: Kim, Hyunjoo, Jeong, Muhah, Na, Do-Hyeong, Ryu, Shin-Hyeon, Jeong, Eun Il, Jung, Kwangmin, Kang, Jaemin, Lee, Ho-June, Sim, Taebo, Yu, Dae-Yeul, Yu, Hee Chul, Cho, Baik-Hwan, Jung, Yong-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117275/
https://www.ncbi.nlm.nih.gov/pubmed/35585049
http://dx.doi.org/10.1038/s41419-022-04921-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117275/
https://www.ncbi.nlm.nih.gov/pubmed/35585049
http://dx.doi.org/10.1038/s41419-022-04921-7

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