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IL-1R-IRAKM-Slc25a1 signaling axis reprograms lipogenesis in adipocytes to promote diet-induced obesity in mice

Toll-like receptors/Interleukin-1 receptor signaling plays an important role in high-fat diet-induced adipose tissue dysfunction contributing to obesity-associated metabolic syndromes. Here, we show an unconventional IL-1R-IRAKM-Slc25a1 signaling axis in adipocytes that reprograms lipogenesis to pr...

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Detalles Bibliográficos
Autores principales: Liu, Weiwei, Zhou, Hao, Wang, Han, Zhang, Quanri, Zhang, Renliang, Willard, Belinda, Liu, Caini, Kang, Zizhen, Li, Xiao, Li, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117277/
https://www.ncbi.nlm.nih.gov/pubmed/35585086
http://dx.doi.org/10.1038/s41467-022-30470-w