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Involvement of FSP1-CoQ(10)-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis

Retinal pigment epithelium (RPE) degeneration plays an important role in a group of retinal disorders such as retinal degeneration (RD) and age-related macular degeneration (AMD). The mechanism of RPE cell death is not yet fully elucidated. Ferroptosis, a novel regulated cell death pathway, particip...

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Detalles Bibliográficos
Autores principales: Yang, Ming, Tsui, Michelle Grace, Tsang, Jessica Kwan Wun, Goit, Rajesh Kumar, Yao, Kwok-Ming, So, Kwok-Fai, Lam, Wai-Ching, Lo, Amy Cheuk Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117320/
https://www.ncbi.nlm.nih.gov/pubmed/35585057
http://dx.doi.org/10.1038/s41419-022-04924-4