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Enhanced anticancer potency with reduced nephrotoxicity of newly synthesized platin-based complexes compared with cisplatin

As a platinum-containing anticancer drug, cisplatin is the keystone for treating many malignancies. Nephrotoxicity is the main dose-limiting toxicity, and several hydration therapies and supplementary strategies are utilized to reduce cisplatin-induced kidney damage, so the discovery and development...

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Detalles Bibliográficos
Autores principales: Salehi, Roya, Abyar, Selda, Ramazani, Fatemeh, Khandar, Ali Akbar, Hosseini-Yazdi, Seyed Abolfazl, White, Jonathan M., Edalati, Mahdi, Kahroba, Houman, Talebi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117324/
https://www.ncbi.nlm.nih.gov/pubmed/35585092
http://dx.doi.org/10.1038/s41598-022-11904-3