Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity

Experimental nephrotic syndrome leads to activation of the epithelial sodium channel (ENaC) by proteolysis and promotes renal sodium retention. The membrane-anchored serine protease prostasin (CAP1/PRSS8) is expressed in the distal nephron and participates in proteolytic ENaC regulation by serving a...

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Detalles Bibliográficos
Autores principales: Essigke, Daniel, Bohnert, Bernhard N., Janessa, Andrea, Wörn, Matthias, Omage, Kingsley, Kalbacher, Hubert, Birkenfeld, Andreas L., Bugge, Thomas H., Szabo, Roman, Artunc, Ferruh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Organ Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117342/
https://www.ncbi.nlm.nih.gov/pubmed/35312839
http://dx.doi.org/10.1007/s00424-022-02682-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117342/
https://www.ncbi.nlm.nih.gov/pubmed/35312839
http://dx.doi.org/10.1007/s00424-022-02682-y

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