Improving Polygenic Prediction in Ancestrally Diverse Populations

Polygenic risk scores (PRS) have attenuated cross-population predictive performance. As existing genome-wide association studies (GWAS) were predominantly conducted in individuals of European descent, the limited transferability of PRS reduces their clinical value in non-European populations and may...

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Detalles Bibliográficos
Autores principales: Ruan, Yunfeng, Lin, Yen-Feng, Feng, Yen-Chen Anne, Chen, Chia-Yen, Lam, Max, Guo, Zhenglin, He, Lin, Sawa, Akira, Martin, Alicia R., Qin, Shengying, Huang, Hailiang, Ge, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117455/
https://www.ncbi.nlm.nih.gov/pubmed/35513724
http://dx.doi.org/10.1038/s41588-022-01054-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117455/
https://www.ncbi.nlm.nih.gov/pubmed/35513724
http://dx.doi.org/10.1038/s41588-022-01054-7

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