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Improving Polygenic Prediction in Ancestrally Diverse Populations

Polygenic risk scores (PRS) have attenuated cross-population predictive performance. As existing genome-wide association studies (GWAS) were predominantly conducted in individuals of European descent, the limited transferability of PRS reduces their clinical value in non-European populations and may...

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Detalles Bibliográficos
Autores principales:	Ruan, Yunfeng, Lin, Yen-Feng, Feng, Yen-Chen Anne, Chen, Chia-Yen, Lam, Max, Guo, Zhenglin, He, Lin, Sawa, Akira, Martin, Alicia R., Qin, Shengying, Huang, Hailiang, Ge, Tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117455/ https://www.ncbi.nlm.nih.gov/pubmed/35513724 http://dx.doi.org/10.1038/s41588-022-01054-7

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