Can Gene Therapy Be Used to Prevent Cancer? Gene Therapy for Aldehyde Dehydrogenase 2 Deficiency

Approximately 8% of the world population and 35 to 45% of East Asians are carriers of the hereditary disorder, aldehyde dehydrogenase 2 (ALDH2) deficiency. ALDH2 plays a central role in the liver to metabolize ethanol. With the common E487K variant, there is a deficiency of ALDH2 function; when etha...

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Detalles Bibliográficos
Autores principales: Montel, Rachel A., Zuluaga, Carlos Munoz, Stiles, Katie M., Crystal, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117562/
https://www.ncbi.nlm.nih.gov/pubmed/34799722
http://dx.doi.org/10.1038/s41417-021-00399-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117562/
https://www.ncbi.nlm.nih.gov/pubmed/34799722
http://dx.doi.org/10.1038/s41417-021-00399-1

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