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Can Gene Therapy Be Used to Prevent Cancer? Gene Therapy for Aldehyde Dehydrogenase 2 Deficiency
Approximately 8% of the world population and 35 to 45% of East Asians are carriers of the hereditary disorder, aldehyde dehydrogenase 2 (ALDH2) deficiency. ALDH2 plays a central role in the liver to metabolize ethanol. With the common E487K variant, there is a deficiency of ALDH2 function; when etha...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117562/ https://www.ncbi.nlm.nih.gov/pubmed/34799722 http://dx.doi.org/10.1038/s41417-021-00399-1 |