Loss of PTEN-Induced Kinase 1 Regulates Oncogenic Ras-Driven Tumor Growth By Inhibiting Mitochondrial Fission

Mitochondrial metabolism and dynamics (fission and fusion) critically regulate cell survival and proliferation, and abnormalities in these pathways are implicated in both neurodegenerative disorders and cancer. Mitochondrial fission is necessary for the growth of mutant Ras-dependent tumors. Here, w...

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Detalles Bibliográficos
Autores principales: Zhu, Dantong, Han, Fengtong, Sun, Liuke, Agnihotri, Sandeep K., Hu, Ying, Büeler, Hansruedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117651/
https://www.ncbi.nlm.nih.gov/pubmed/35600352
http://dx.doi.org/10.3389/fonc.2022.893396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117651/
https://www.ncbi.nlm.nih.gov/pubmed/35600352
http://dx.doi.org/10.3389/fonc.2022.893396

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