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METTL3-mediated macrophage exosomal NEAT1 contributes to hepatic fibrosis progression through Sp1/TGF-β1/Smad signaling pathway

Hepatic fibrosis (HF) is caused by chronic hepatic injury and is characterized by hepatic stellate cells (HSCs) activation. Studies focusing on the function of exosomes derived from macrophages in HF progression are limited. This study aims to identify the roles of exosomal NEAT1 derived from macrop...

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Detalles Bibliográficos
Autores principales: Shu, Bo, Zhang, Rui-Zhi, Zhou, Ying-Xia, He, Chao, Yang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117676/
https://www.ncbi.nlm.nih.gov/pubmed/35585044
http://dx.doi.org/10.1038/s41420-022-01036-y