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A Comparison of Methods for Gene-Based Testing That Account for Linkage Disequilibrium
Controlling the type I error rate while retaining sufficient power is a major concern in genome-wide association studies, which nowadays often examine more than a million single-nucleotide polymorphisms (SNPs) simultaneously. Methods such as the Bonferroni correction can lead to a considerable decre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117705/ https://www.ncbi.nlm.nih.gov/pubmed/35601489 http://dx.doi.org/10.3389/fgene.2022.867724 |