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ATP spreads inflammation to other limbs through crosstalk between sensory neurons and interneurons

Neural circuits between lesions are one mechanism through which local inflammation spreads to remote positions. Here, we show the inflammatory signal on one side of the joint is spread to the other side via sensory neuron–interneuron crosstalk, with ATP at the core. Surgical ablation or pharmacologi...

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Detalles Bibliográficos
Autores principales: Hasebe, Rie, Murakami, Kaoru, Harada, Masaya, Halaka, Nada, Nakagawa, Hiroshi, Kawano, Fuminori, Ohira, Yoshinobu, Kawamoto, Tadafumi, Yull, Fiona E., Blackwell, Timothy S., Nio-Kobayashi, Junko, Iwanaga, Toshihiko, Watanabe, Masahiko, Watanabe, Nobuhiro, Hotta, Harumi, Yamashita, Toshihide, Kamimura, Daisuke, Tanaka, Yuki, Murakami, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117706/
https://www.ncbi.nlm.nih.gov/pubmed/35579694
http://dx.doi.org/10.1084/jem.20212019