Multinuclear Metal-Binding Ability of the N-Terminal Region of Human Copper Transporter Ctr1: Dependence Upon pH and Metal Oxidation State

The 14mer peptide corresponding to the N-terminal region of human copper transporter Ctr1 was used to investigate the intricate mechanism of metal binding to this plasma membrane permease responsible for copper import in eukaryotic cells. The peptide contains a high-affinity ATCUN Cu(II)/Ni(II)-sele...

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Detalles Bibliográficos
Autores principales: Nardella, Maria Incoronata, Fortino, Mariagrazia, Barbanente, Alessandra, Natile, Giovanni, Pietropaolo, Adriana, Arnesano, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117721/
https://www.ncbi.nlm.nih.gov/pubmed/35601835
http://dx.doi.org/10.3389/fmolb.2022.897621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117721/
https://www.ncbi.nlm.nih.gov/pubmed/35601835
http://dx.doi.org/10.3389/fmolb.2022.897621

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