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The TRiCky Business of Protein Folding in Health and Disease

Maintenance of the cellular proteome or proteostasis is an essential process that when deregulated leads to diseases like neurological disorders and cancer. Central to proteostasis are the molecular chaperones that fold proteins into functional 3-dimensional (3D) shapes and prevent protein aggregati...

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Detalles Bibliográficos
Autores principales: Ghozlan, Heba, Cox, Amanda, Nierenberg, Daniel, King, Stephen, Khaled, Annette R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117761/
https://www.ncbi.nlm.nih.gov/pubmed/35602608
http://dx.doi.org/10.3389/fcell.2022.906530