Cargando…
Whole exome sequencing reveals the genetic heterogeneity and evolutionary history of primary gliomas and matched recurrences
Diffuse glioma is a highly heterogeneous central nervous system tumor that is refractory to conventional therapy. Residual glioma cells escape from surgery and chemoradiotherapy, leading to lethal recurrence. Understanding the molecular mechanism of this recurrence process is critical to the develop...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117816/ https://www.ncbi.nlm.nih.gov/pubmed/35615029 http://dx.doi.org/10.1016/j.csbj.2022.04.034 |