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Whole exome sequencing reveals the genetic heterogeneity and evolutionary history of primary gliomas and matched recurrences

Diffuse glioma is a highly heterogeneous central nervous system tumor that is refractory to conventional therapy. Residual glioma cells escape from surgery and chemoradiotherapy, leading to lethal recurrence. Understanding the molecular mechanism of this recurrence process is critical to the develop...

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Detalles Bibliográficos
Autores principales:	Xu, Peng-Fei, Li, Cong, Xi, Shao-Yan, Chen, Fu-Rong, Wang, Jing, Zhang, Zhi-Qiang, Liu, Yan, Li, Xin, Chen, Zhong-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117816/ https://www.ncbi.nlm.nih.gov/pubmed/35615029 http://dx.doi.org/10.1016/j.csbj.2022.04.034

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