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Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression

BACKGROUND & AIMS: Liver fibrosis represents a hallmark of most chronic liver diseases (CLD) triggered by recurrent liver injury and subsequent myofibroblast transdifferentiations of resident hepatic stellate cells (HSCs). Mannan-binding lectin (MBL) is potentially involved in hepatic fibrosis i...

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Detalles Bibliográficos
Autores principales: Luo, Jialiang, Li, Lei, Chang, Bo, Zhu, Zhengyumeng, Deng, Fan, Hu, Mengyao, Yu, Yu, Lu, Xiao, Chen, Zhengliang, Zuo, Daming, Zhou, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117817/
https://www.ncbi.nlm.nih.gov/pubmed/35381393
http://dx.doi.org/10.1016/j.jcmgh.2022.03.011