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Targeting USP9X–AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma
BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is a highly heterogeneous solid tumor with high morbidity and mortality. AT-rich interaction domain 1A (ARID1A) accounts for up to 10% of mutations in liver cancer, however, its role in HCC remains controversial, and no targeted therapy has been...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117818/ https://www.ncbi.nlm.nih.gov/pubmed/35390516 http://dx.doi.org/10.1016/j.jcmgh.2022.03.009 |