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Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8(+) T cell exhaustion
Exhausted CD8(+) T cells with limited effector functions and high expression of multiple co-inhibitory receptors are one of the main barriers hindering antitumor immunity. The NADase CD38 has received considerable attention as a biomarker of CD8(+) T cell exhaustion, but it remains unclear whether t...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117873/ https://www.ncbi.nlm.nih.gov/pubmed/35602958 http://dx.doi.org/10.1016/j.isci.2022.104347 |