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Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8(+) T cell exhaustion

Exhausted CD8(+) T cells with limited effector functions and high expression of multiple co-inhibitory receptors are one of the main barriers hindering antitumor immunity. The NADase CD38 has received considerable attention as a biomarker of CD8(+) T cell exhaustion, but it remains unclear whether t...

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Detalles Bibliográficos
Autores principales: Ma, Kaili, Sun, Lina, Shen, Mingjing, Zhang, Xin, Xiao, Zhen, Wang, Jiajia, Liu, Xiaowei, Jiang, Kanqiu, Xiao-Feng Qin, F., Guo, Feng, Zhang, Baojun, Zhang, Lianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117873/
https://www.ncbi.nlm.nih.gov/pubmed/35602958
http://dx.doi.org/10.1016/j.isci.2022.104347