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Generation, expansion, and drug treatment of hematopoietic progenitor cells derived from human iPSCs

Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome that can progress to acute myeloid leukemia (CN/AML). Patient material to study leukemogenesis, especially hematopoietic progenitor cells (HPCs) is limited and hard to access. We have established a protocol for generat...

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Detalles Bibliográficos
Autores principales: Dannenmann, Benjamin, Skokowa, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117918/
https://www.ncbi.nlm.nih.gov/pubmed/35600931
http://dx.doi.org/10.1016/j.xpro.2022.101400