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Generation, expansion, and drug treatment of hematopoietic progenitor cells derived from human iPSCs
Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome that can progress to acute myeloid leukemia (CN/AML). Patient material to study leukemogenesis, especially hematopoietic progenitor cells (HPCs) is limited and hard to access. We have established a protocol for generat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117918/ https://www.ncbi.nlm.nih.gov/pubmed/35600931 http://dx.doi.org/10.1016/j.xpro.2022.101400 |