Simulation of receptor triggering by kinetic segregation shows role of oligomers and close contacts

The activation of T cells, key players of the immune system, involves local evacuation of phosphatase CD45 from a region of the T cell’s surface, segregating it from the T cell receptor. What drives this evacuation? In the presence of antigen, what ensures evacuation happens in the subsecond timesca...

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Detalles Bibliográficos
Autores principales: Taylor, Robert, Allard, Jun, Read, Elizabeth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117938/
https://www.ncbi.nlm.nih.gov/pubmed/35367423
http://dx.doi.org/10.1016/j.bpj.2022.03.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117938/
https://www.ncbi.nlm.nih.gov/pubmed/35367423
http://dx.doi.org/10.1016/j.bpj.2022.03.033

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