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Simulation of receptor triggering by kinetic segregation shows role of oligomers and close contacts
The activation of T cells, key players of the immune system, involves local evacuation of phosphatase CD45 from a region of the T cell’s surface, segregating it from the T cell receptor. What drives this evacuation? In the presence of antigen, what ensures evacuation happens in the subsecond timesca...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117938/ https://www.ncbi.nlm.nih.gov/pubmed/35367423 http://dx.doi.org/10.1016/j.bpj.2022.03.033 |