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mTORC1 is a key regulator that mediates OGD- and TGFβ1-induced myofibroblast transformation and chondroitin-4-sulfate expression in cardiac fibroblasts

Ischemia-reperfusion infarct-derived chondroitin sulfate proteoglycans (CSPGs) are important for sustaining denervation of the infarct. Sympathetic denervation within the heart after myocardial infarction (MI) predicts the probability of a higher risk for serious ventricular arrhythmias. Chondroitin...

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Detalles Bibliográficos
Autores principales: Li, Chao, Zhang, Zheng, Peng, Yu, Zhang, Yanying, Kang, Wanrong, Li, Yingdong, Hai, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117951/
https://www.ncbi.nlm.nih.gov/pubmed/35601064
http://dx.doi.org/10.3892/etm.2022.11340