Stool is a sensitive and noninvasive source of DNA for monitoring expansion in repeat expansion disease mouse models

Repeat expansion diseases are a large group of human genetic disorders caused by expansion of a specific short tandem repeat tract. Expansion in somatic cells affects age of onset and disease severity in some of these disorders. However, alleles in DNA derived from blood, a commonly used source of D...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaonan, McHugh, Cassandra, Coffey, Sydney R., Jimenez, Diego Antonio, Adams, Elizabeth, Carroll, Jeffrey B., Usdin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118036/
https://www.ncbi.nlm.nih.gov/pubmed/35403689
http://dx.doi.org/10.1242/dmm.049453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118036/
https://www.ncbi.nlm.nih.gov/pubmed/35403689
http://dx.doi.org/10.1242/dmm.049453

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