Inhibition of activin A receptor signalling attenuates age-related pathological cardiac remodelling

In the heart, ageing is associated with DNA damage, oxidative stress, fibrosis and activation of the activin signalling pathway, leading to cardiac dysfunction. The cardiac effects of activin signalling blockade in progeria are unknown. This study investigated the cardiac effects of progeria induced...

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Detalles Bibliográficos
Autores principales: Clavere, Nicolas G., Alqallaf, Ali, Rostron, Kerry A., Parnell, Andrew, Mitchell, Robert, Patel, Ketan, Boateng, Samuel Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118092/
https://www.ncbi.nlm.nih.gov/pubmed/35380160
http://dx.doi.org/10.1242/dmm.049424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118092/
https://www.ncbi.nlm.nih.gov/pubmed/35380160
http://dx.doi.org/10.1242/dmm.049424

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