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DNA-Binding Properties of Bis-N-substituted Tetrandrine Derivatives

[Image: see text] A series of bis-N-substituted tetrandrine derivatives carrying different aromatic substituents attached to both nitrogen atoms of the natural alkaloid were studied with double-stranded model DNAs (dsDNAs) to examine the binding properties and mechanism. Variable-temperature molecul...

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Detalles Bibliográficos
Autores principales: González-Martínez, Sandra Mónica, Valencia-Ochoa, Drochss Pettry, Gálvez-Ruiz, Juan Carlos, Leyva-Peralta, Mario Alberto, Juárez-Sánchez, Octavio, Islas-Osuna, María A., Calvillo-Páez, Viviana Isabel, Höpfl, Herbert, Íñiguez-Palomares, Ramón, Rocha-Alonzo, Fernando, Ochoa Lara, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118212/
https://www.ncbi.nlm.nih.gov/pubmed/35601331
http://dx.doi.org/10.1021/acsomega.2c00225