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A decision-theoretic approach to Bayesian clinical trial design and evaluation of robustness to prior-data conflict

Bayesian clinical trials allow taking advantage of relevant external information through the elicitation of prior distributions, which influence Bayesian posterior parameter estimates and test decisions. However, incorporation of historical information can have harmful consequences on the trial’s fr...

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Detalles Bibliográficos
Autores principales: Calderazzo, Silvia, Wiesenfarth, Manuel, Kopp-Schneider, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118338/
https://www.ncbi.nlm.nih.gov/pubmed/32735010
http://dx.doi.org/10.1093/biostatistics/kxaa027