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A decision-theoretic approach to Bayesian clinical trial design and evaluation of robustness to prior-data conflict
Bayesian clinical trials allow taking advantage of relevant external information through the elicitation of prior distributions, which influence Bayesian posterior parameter estimates and test decisions. However, incorporation of historical information can have harmful consequences on the trial’s fr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118338/ https://www.ncbi.nlm.nih.gov/pubmed/32735010 http://dx.doi.org/10.1093/biostatistics/kxaa027 |