Quantitative single-cell transcriptome-based ranking of engineered AAVs in human retinal explants

Gene therapy is a rapidly developing field, and adeno-associated viruses (AAVs) are a leading viral-vector candidate for therapeutic gene delivery. Newly engineered AAVs with improved abilities are now entering the clinic. It has proven challenging, however, to predict the translational potential of...

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Detalles Bibliográficos
Autores principales: Xi, Zhouhuan, Öztürk, Bilge E., Johnson, Molly E., Turunç, Serhan, Stauffer, William R., Byrne, Leah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118357/
https://www.ncbi.nlm.nih.gov/pubmed/35615708
http://dx.doi.org/10.1016/j.omtm.2022.04.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118357/
https://www.ncbi.nlm.nih.gov/pubmed/35615708
http://dx.doi.org/10.1016/j.omtm.2022.04.014

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