Hydrosoluble Perylene Monoimide-Based Telomerase Inhibitors with Diminished Cytotoxicity

[Image: see text] Telomerase is essential for the immortality characteristics of most cancers. Telomerase-specific inhibitors should render cancer cells to replicative senescence without acute cytotoxicity. Perylene-based G-quadruplex (G4) ligands are widely studied as telomerase inhibitors. Most re...

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Detalles Bibliográficos
Autores principales: Thaichana, Pak, Summart, Ratasark, Dejkriengkraikul, Pornngarm, Meepowpan, Puttinan, Lee, T. Randall, Tuntiwechapikul, Wirote
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118414/
https://www.ncbi.nlm.nih.gov/pubmed/35601338
http://dx.doi.org/10.1021/acsomega.2c01343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118414/
https://www.ncbi.nlm.nih.gov/pubmed/35601338
http://dx.doi.org/10.1021/acsomega.2c01343

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