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Laminin-integrin a6b4 interaction activates notch signaling to facilitate bladder cancer development

BACKGROUND: Laminins are high-molecular weight (400 ~ 900 kDa) proteins in extracellular matrix, which serve as major component of the basal lamina, and play a crucial role in promoting tumor cell migration. This study aimed at characterizing the role of laminin in promoting cancer development, and...

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Detalles Bibliográficos
Autores principales: Hao, Nan, Yang, Daming, Liu, Tianpei, Liu, Shucheng, Lu, Xinsheng, Chen, Libo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118635/
https://www.ncbi.nlm.nih.gov/pubmed/35585515
http://dx.doi.org/10.1186/s12885-022-09645-7