Metabolic changes accompanying the loss of fumarate hydratase and malate–quinone oxidoreductase in the asexual blood stage of Plasmodium falciparum

In the glucose-rich milieu of red blood cells, asexually replicating malarial parasites mainly rely on glycolysis for ATP production, with limited carbon flux through the mitochondrial tricarboxylic acid (TCA) cycle. By contrast, gametocytes and mosquito-stage parasites exhibit an increased dependen...

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Detalles Bibliográficos
Autores principales: Rajaram, Krithika, Tewari, Shivendra G., Wallqvist, Anders, Prigge, Sean T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118666/
https://www.ncbi.nlm.nih.gov/pubmed/35398098
http://dx.doi.org/10.1016/j.jbc.2022.101897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118666/
https://www.ncbi.nlm.nih.gov/pubmed/35398098
http://dx.doi.org/10.1016/j.jbc.2022.101897

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