Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15

Introduction of fetal cell cycle genes into damaged adult hearts has emerged as a promising strategy for stimulating proliferation and regeneration of postmitotic adult cardiomyocytes. We have recently identified Fam64a as a fetal-specific cell cycle promoter in cardiomyocytes. Here, we analyzed tra...

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Detalles Bibliográficos
Autores principales: Hashimoto, Ken, Kodama, Aya, Ohira, Momoko, Kimoto, Misaki, Nakagawa, Reiko, Usui, Yuu, Ujihara, Yoshihiro, Hanashima, Akira, Mohri, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118685/
https://www.ncbi.nlm.nih.gov/pubmed/35602953
http://dx.doi.org/10.1016/j.isci.2022.104337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118685/
https://www.ncbi.nlm.nih.gov/pubmed/35602953
http://dx.doi.org/10.1016/j.isci.2022.104337

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