Ym1(+) macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic cancer

Desmoplasia around pancreatic lesions is a barrier for immune cells and a hallmark of developing and established pancreatic cancer. However, the contribution of the innate immune system to this process is ill-defined. Using the KC mouse model and primary cells in vitro, we show that alternatively ac...

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Detalles Bibliográficos
Autores principales: Fleming Martinez, Alicia K., Döppler, Heike R., Bastea, Ligia I., Edenfield, Brandy H., Liou, Geou-Yarh, Storz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118688/
https://www.ncbi.nlm.nih.gov/pubmed/35602933
http://dx.doi.org/10.1016/j.isci.2022.104327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118688/
https://www.ncbi.nlm.nih.gov/pubmed/35602933
http://dx.doi.org/10.1016/j.isci.2022.104327

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