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Ym1(+) macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic cancer
Desmoplasia around pancreatic lesions is a barrier for immune cells and a hallmark of developing and established pancreatic cancer. However, the contribution of the innate immune system to this process is ill-defined. Using the KC mouse model and primary cells in vitro, we show that alternatively ac...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118688/ https://www.ncbi.nlm.nih.gov/pubmed/35602933 http://dx.doi.org/10.1016/j.isci.2022.104327 |