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Differentially methylated CpGs in response to growth hormone administration in children with idiopathic short stature

BACKGROUND: Recombinant human growth hormone (rhGH) has shown a great growth-promoting potential in children with idiopathic short stature (ISS). However, the response to rhGH differs across individuals, largely due to genetic and epigenetic heterogeneity. Since epigenetic marks on the methylome can...

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Detalles Bibliográficos
Autores principales: Shao, Xiaojian, Le Stunff, Catherine, Cheung, Warren, Kwan, Tony, Lathrop, Mark, Pastinen, Tomi, Bougnères, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118695/
https://www.ncbi.nlm.nih.gov/pubmed/35585611
http://dx.doi.org/10.1186/s13148-022-01281-z