KDM3A-mediated SP1 activates PFKFB4 transcription to promote aerobic glycolysis in osteosarcoma and augment tumor development

BACKGROUND: Lysine-specific histone demethylase 3A (KDM3A) is a potent histone modifier that is frequently implicated in the progression of several malignancies. However, its role in aerobic glycolysis of osteosarcoma (OS) remains unclear. METHODS: KDM3A expression in OS tissues was determined by im...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118730/
https://www.ncbi.nlm.nih.gov/pubmed/35590288
http://dx.doi.org/10.1186/s12885-022-09636-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118730/
https://www.ncbi.nlm.nih.gov/pubmed/35590288
http://dx.doi.org/10.1186/s12885-022-09636-8

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