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Notch ankyrin domain: evolutionary rise of a thermodynamic sensor

Notch signalling pathway plays a key role in metazoan biology by contributing to resolution of binary decisions in the life cycle of cells during development. Outcomes such as proliferation/differentiation dichotomy are resolved by transcriptional remodelling that follows a switch from Notch(on) to...

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Detalles Bibliográficos
Autores principales: Vujovic, Filip, Hunter, Neil, Farahani, Ramin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118731/
https://www.ncbi.nlm.nih.gov/pubmed/35585601
http://dx.doi.org/10.1186/s12964-022-00886-4