PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment

Chemokines are highly expressed in tumor microenvironment and play a critical role in all aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, activation of cancer-associated fibroblasts, angiogenesis, metastasis, and growth. Poly (ADP-ribose) polymerase (PARP) is a m...

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Detalles Bibliográficos
Autores principales: Johnson, Sarah, Karpova, Yaroslava, Guo, Danping, Ghatak, Atreyi, Markov, Dmitriy A., Tulin, Alexei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118775/
https://www.ncbi.nlm.nih.gov/pubmed/35585513
http://dx.doi.org/10.1186/s12885-022-09651-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118775/
https://www.ncbi.nlm.nih.gov/pubmed/35585513
http://dx.doi.org/10.1186/s12885-022-09651-9

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