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PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment

Chemokines are highly expressed in tumor microenvironment and play a critical role in all aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, activation of cancer-associated fibroblasts, angiogenesis, metastasis, and growth. Poly (ADP-ribose) polymerase (PARP) is a m...

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Detalles Bibliográficos
Autores principales:	Johnson, Sarah, Karpova, Yaroslava, Guo, Danping, Ghatak, Atreyi, Markov, Dmitriy A., Tulin, Alexei V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118775/ https://www.ncbi.nlm.nih.gov/pubmed/35585513 http://dx.doi.org/10.1186/s12885-022-09651-9

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