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Bulk and single-cell transcriptome profiling reveal necroptosis-based molecular classification, tumor microenvironment infiltration characterization, and prognosis prediction in colorectal cancer

BACKGROUND: Necroptosis is a new form of programmed cell death that is associated with cancer initiation, progression, immunity, and chemoresistance. However, the roles of necroptosis-related genes (NRGs) in colorectal cancer (CRC) have not been explored comprehensively. METHODS: In this study, we o...

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Detalles Bibliográficos
Autores principales: Luo, Wenqin, Xiang, Wenqiang, Gan, Lu, Che, Ji, Li, Jing, Wang, Yichao, Han, Lingyu, Gu, Ruiqi, Ye, Li, Wang, Renjie, Zhang, Xiuping, Xu, Ye, Dai, Weixing, Mo, Shaobo, Li, Qingguo, Cai, Guoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118791/
https://www.ncbi.nlm.nih.gov/pubmed/35590418
http://dx.doi.org/10.1186/s12967-022-03431-6