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Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1

Protein phosphatase 2A (PP2A) is a serine/threonine dephosphorylating enzyme complex that plays numerous roles in biological processes, including cell growth and metabolism. However, its specific actions in many of these critical pathways are unclear. To explore mechanisms underlying metabolic enzym...

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Detalles Bibliográficos
Autores principales: Chen, Liping, Guo, Ping, Li, Wenxue, Jiang, Xinhang, Zhao, Qun, Li, Daochuan, Wang, Qing, Xiao, Yongmei, Xing, Xiumei, Pang, Yaqin, Aschner, Michael, Zhang, Lihua, Chen, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118923/
https://www.ncbi.nlm.nih.gov/pubmed/35405096
http://dx.doi.org/10.1016/j.jbc.2022.101918